Principal Engineer Global Downstream Process Engineering Job Listing at Genzyme Corporation in Framingham, MA

Biotechnology, Pharmaceutical

Principal Engineer, Global Downstream Process Engineering-32062

Description
Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. We accomplish our goals through world-class research, collaboration with the global patient community, and with the compassion and commitment of our employees. With a focus on rare diseases and multiple sclerosis, we are dedicated to making a positive impact on the lives of the patients and families we serve. Genzyme's portfolio of transformative therapies, which are marketed in countries around the world, represent groundbreaking and life-saving advances in medicine. As a Sanofi company, Genzyme benefits from the reach and resources of one of the world's largest pharmaceutical companies, with a shared commitment to improving the lives of patients. Learn more at www.genzyme.com..

Principal Engineer, Downstream Process Engineering

We are seeking a highly motivated, highly organized, self-directed and flexible individual who can lead and set direction, demonstrating broad depth of knowledge in Downstream Process Engineering (Purification). This person will be viewed as the subject matter expert (SME) in this area. The successful candidate will report to the Director of Global Engineering. This position is based in Framingham, Massachusetts and requires the ability to manage within a complex, fast paced, dynamic and highly matrixed global environment.

The successful candidate will be responsible for the development, implementation and management of the Global Downstream Process Engineering (Purification) program at Genzyme, development and management of the Global Engineering Downstream Process Engineering (Purification) Team, and management and provision of technical peer reviews and support to projects and site engineering teams as required.

The successful candidate will be expected to quickly engage with key stakeholders - internal and external, to clearly identify the critical issues and formulate solutions that will deliver value to the business. This should be done in a proactive way that involves the stakeholder in the development of the best valued engineering solution, which meets the stakeholder's needs. The engineer will establish and clearly communicate business goals for entire global network in a framework that the individual members of the network can understand relative to their accountabilities and expectations for achievement of those goals.

The successful candidate will direct performance, manage the global network, develop key strategies and work collaboratively with project teams and sites. A key skill in the role is the ability to incorporate the business needs and constraints with the end users needs. It is essential that successful candidate demonstrate leadership and foster collaboration within the network and develop a strong relationship with Genzyme personnel and supporting contractors.

Global Downstream Process Engineering (Purification) Team Development and Management

The successful candidate will establish the foundation of technical subject matter experts to allow the Global Downstream Process Engineering (Purification) network to deliver robust Purification solutions, cost effectively, understanding and ensuring compliance with international regulations and adherence to Genzyme quality standards. This individual will define the team structure, and identify and manage the Subject Matter Experts from within the Global Engineering network, or using external resources, as appropriate.

Global Downstream Process Engineering (Purification) Technical Support

In this role, the successful candidate will be responsible for providing technical support to projects or site engineers, as required. The individual will assess and manage risk effectively such that projects progress to meet the business needs. These risks may be assessed and managed with limited information, and under time constraints associated with responsibility for multiple projects. It is vital that the successful candidate have the ability to create an environment in which the project team is empowered to make decisions and move projects forward.
The SME is responsible for providing direction and technical leadership for the design and development of Purification manufacturing equipment, including engineering, startup, commissioning and qualification of buffer preparation, buffer hold, purification and WIP storage. Additionally, the SME will be responsible for leading the Global Engineering Downstream Process Engineering (Purification) Network to address complex problems equipment related to Purification.

Travel will be required both domestically and internationally. Some weekend travel may be required.

Qualifications
Basic Qualifications:

• BS or MS degree in an Engineering discipline with a minimum of 12-15 years of progressive experience in the Biotechnology, Biopharmaceutical or Pharmaceutical industries

Successful Candidates Must Also Possess:

• Experience in leading and/or influencing multi-disciplinary global groups in a fast paced changeable environment
• Strong leadership, relationship management, and organizational planning and project management skills, in addition to technical knowledge
• Ability to influence sites, suppliers and colleagues into adopting "best practice" and a proven track record of building and growing "best in class" engineering teams
• Experience with Protein Purification and Chromatography equipment
• Experience in utility, facility, and equipment design and operation, as well as experience in cGMP manufacturing environments related to the design of equipment, to maintain sterile operations
• Excellent communication skills - verbal, written, listening and interpersonal with the ablilty to transfer knowledge to others portraying confidence to sites globally that you and your team are the experts and can deliver
• Good Supplier Relationship Management competence will be required
• Attentive to cultural sensitivities

Job : Engineer
Primary Location : United States-Massachusetts-Framingham

Job Posting : Jan 22, 2013

Shift : Day Job
Job Type : Regular
Employee Status : Regular